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Non-synonymous sequence variants within the oxygen-dependent degradation domain of the HIF1A gene are not associated with pre-eclampsia in the Finnish population

BACKGROUND: Reduced placental perfusion predisposes to the maternal syndrome pre-eclampsia characterized by systemically reduced perfusion. Considerable data support the role of angiogenic factors in the development of the maternal syndrome. Hypoxia-inducible factor (HIF-1) mediates the cellular res...

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Detalles Bibliográficos
Autores principales:	Heino, Sanna, Kaare, Milja, Andersson, Sture, Laivuori, Hannele
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600634/ https://www.ncbi.nlm.nih.gov/pubmed/18980686 http://dx.doi.org/10.1186/1471-2350-9-96

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