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Non-synonymous sequence variants within the oxygen-dependent degradation domain of the HIF1A gene are not associated with pre-eclampsia in the Finnish population
BACKGROUND: Reduced placental perfusion predisposes to the maternal syndrome pre-eclampsia characterized by systemically reduced perfusion. Considerable data support the role of angiogenic factors in the development of the maternal syndrome. Hypoxia-inducible factor (HIF-1) mediates the cellular res...
Autores principales: | Heino, Sanna, Kaare, Milja, Andersson, Sture, Laivuori, Hannele |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600634/ https://www.ncbi.nlm.nih.gov/pubmed/18980686 http://dx.doi.org/10.1186/1471-2350-9-96 |
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