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High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability

High-level microsatellite instability (MSI-H) in colorectal cancer accounts for about 12% of colorectal cancers and is typically associated with a dense infiltration with cytotoxic CD8-positive lymphocytes. The role of regulatory T cells that may interfere with the host's antitumoural immune re...

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Detalles Bibliográficos
Autores principales: Michel, S, Benner, A, Tariverdian, M, Wentzensen, N, Hoefler, P, Pommerencke, T, Grabe, N, von Knebel Doeberitz, M, Kloor, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600708/
https://www.ncbi.nlm.nih.gov/pubmed/18985040
http://dx.doi.org/10.1038/sj.bjc.6604756