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Flanking p10 contribution and sequence bias in matrix based epitope prediction: revisiting the assumption of independent binding pockets

BACKGROUND: Eluted natural peptides from major histocompatibility molecules show patterns of conserved residues. Crystallographic structures show that the bound peptide in class II major histocompatibility complex adopts a near uniform polyproline II-like conformation. This way allele-specific favou...

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Detalles Bibliográficos
Autor principal: Parry, Christian S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600787/
https://www.ncbi.nlm.nih.gov/pubmed/18925947
http://dx.doi.org/10.1186/1472-6807-8-44