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Flanking p10 contribution and sequence bias in matrix based epitope prediction: revisiting the assumption of independent binding pockets
BACKGROUND: Eluted natural peptides from major histocompatibility molecules show patterns of conserved residues. Crystallographic structures show that the bound peptide in class II major histocompatibility complex adopts a near uniform polyproline II-like conformation. This way allele-specific favou...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600787/ https://www.ncbi.nlm.nih.gov/pubmed/18925947 http://dx.doi.org/10.1186/1472-6807-8-44 |