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New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report
INTRODUCTION: Devic's neuromyelitis optica is an inflammatory demyelinating disease that targets the optic nerves and spinal cord. It has a worldwide distribution and distinctive features that distinguish it from multiple sclerosis. There has been no previous report of neuromyelitis optica from...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600793/ https://www.ncbi.nlm.nih.gov/pubmed/19014638 http://dx.doi.org/10.1186/1752-1947-2-348 |
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author | Komolafe, Morenikeji A Komolafe, Edward O Sunmonu, Taofiki A Olateju, SO Asaleye, CM Adesina, Olufemi A Badmus, SA |
author_facet | Komolafe, Morenikeji A Komolafe, Edward O Sunmonu, Taofiki A Olateju, SO Asaleye, CM Adesina, Olufemi A Badmus, SA |
author_sort | Komolafe, Morenikeji A |
collection | PubMed |
description | INTRODUCTION: Devic's neuromyelitis optica is an inflammatory demyelinating disease that targets the optic nerves and spinal cord. It has a worldwide distribution and distinctive features that distinguish it from multiple sclerosis. There has been no previous report of neuromyelitis optica from our practice environment, and we are not aware of any case associated with antiphospholipid syndrome in an African person. CASE PRESENTATION: We report the case of a 28-year-old Nigerian woman who presented with neck pain, paroxysmal tonic spasms, a positive Lhermitte's sign and spastic quadriplegia. She later developed bilateral optic neuritis and had clinical and biochemical features of antiphospholipid syndrome. Her initial magnetic resonance imaging showed a central linear hyperintense focus in the intramedullary portion of C2 to C4. Repeat magnetic resonance imaging after treatment revealed resolution of the signal intensity noticed earlier. CONCLUSION: Neuromyelitis optica should be considered in the differential diagnoses of acute myelopathy in Africans. We also highlight the unusual association with antiphospholipid syndrome. Physicians should screen such patients for autoimmune disorders. |
format | Text |
id | pubmed-2600793 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26007932008-12-12 New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report Komolafe, Morenikeji A Komolafe, Edward O Sunmonu, Taofiki A Olateju, SO Asaleye, CM Adesina, Olufemi A Badmus, SA J Med Case Reports Case Report INTRODUCTION: Devic's neuromyelitis optica is an inflammatory demyelinating disease that targets the optic nerves and spinal cord. It has a worldwide distribution and distinctive features that distinguish it from multiple sclerosis. There has been no previous report of neuromyelitis optica from our practice environment, and we are not aware of any case associated with antiphospholipid syndrome in an African person. CASE PRESENTATION: We report the case of a 28-year-old Nigerian woman who presented with neck pain, paroxysmal tonic spasms, a positive Lhermitte's sign and spastic quadriplegia. She later developed bilateral optic neuritis and had clinical and biochemical features of antiphospholipid syndrome. Her initial magnetic resonance imaging showed a central linear hyperintense focus in the intramedullary portion of C2 to C4. Repeat magnetic resonance imaging after treatment revealed resolution of the signal intensity noticed earlier. CONCLUSION: Neuromyelitis optica should be considered in the differential diagnoses of acute myelopathy in Africans. We also highlight the unusual association with antiphospholipid syndrome. Physicians should screen such patients for autoimmune disorders. BioMed Central 2008-11-17 /pmc/articles/PMC2600793/ /pubmed/19014638 http://dx.doi.org/10.1186/1752-1947-2-348 Text en Copyright © 2008 Komolafe et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Komolafe, Morenikeji A Komolafe, Edward O Sunmonu, Taofiki A Olateju, SO Asaleye, CM Adesina, Olufemi A Badmus, SA New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report |
title | New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report |
title_full | New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report |
title_fullStr | New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report |
title_full_unstemmed | New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report |
title_short | New onset neuromyelitis optica in a young Nigerian woman with possible antiphospholipid syndrome: a case report |
title_sort | new onset neuromyelitis optica in a young nigerian woman with possible antiphospholipid syndrome: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600793/ https://www.ncbi.nlm.nih.gov/pubmed/19014638 http://dx.doi.org/10.1186/1752-1947-2-348 |
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