Characterization of biofilm matrix, degradation by DNase treatment and evidence of capsule downregulation in Streptococcus pneumoniae clinical isolates

BACKGROUND: Streptococcus pneumoniae is a common respiratory pathogen and a major causative agent of respiratory infections, including otitis media (OM). Pneumococcal biofilms have been demonstrated on biopsies of the middle ear mucosa in children receiving tympanostomy tubes, supporting the hypothe...

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Detalles Bibliográficos
Autores principales: Hall-Stoodley, Luanne, Nistico, Laura, Sambanthamoorthy, Karthik, Dice, Bethany, Nguyen, Duc, Mershon, William J, Johnson, Candice, Ze Hu, Fen, Stoodley, Paul, Ehrlich, Garth D, Post, J Christopher
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600794/
https://www.ncbi.nlm.nih.gov/pubmed/18842140
http://dx.doi.org/10.1186/1471-2180-8-173

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