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Peak intensity prediction in MALDI-TOF mass spectrometry: A machine learning study to support quantitative proteomics

BACKGROUND: Mass spectrometry is a key technique in proteomics and can be used to analyze complex samples quickly. One key problem with the mass spectrometric analysis of peptides and proteins, however, is the fact that absolute quantification is severely hampered by the unclear relationship between...

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Detalles Bibliográficos
Autores principales: Timm, Wiebke, Scherbart, Alexandra, Böcker, Sebastian, Kohlbacher, Oliver, Nattkemper, Tim W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600826/
https://www.ncbi.nlm.nih.gov/pubmed/18937839
http://dx.doi.org/10.1186/1471-2105-9-443