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An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10

BACKGROUND: A major challenge lies in understanding the complexities of gene regulation. Mutation of the transcription factor SOX10 is associated with several human diseases. The disease phenotypes reflect the function of SOX10 in diverse tissues including the neural crest, central nervous system an...

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Detalles Bibliográficos
Autores principales: Dutton, James R, Antonellis, Anthony, Carney, Thomas J, Rodrigues, Frederico SLM, Pavan, William J, Ward, Andrew, Kelsh, Robert N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2601039/
https://www.ncbi.nlm.nih.gov/pubmed/18950534
http://dx.doi.org/10.1186/1471-213X-8-105