Cargando…
Selective androgen receptor modulators in preclinical and clinical development
Androgen receptor (AR) plays a critical role in the function of several organs including primary and accessory sexual organs, skeletal muscle, and bone, making it a desirable therapeutic target. Selective androgen receptor modulators (SARMs) bind to the AR and demonstrate osteo- and myo-anabolic act...
Autores principales: | Narayanan, Ramesh, Mohler, Michael L., Bohl, Casey E., Miller, Duane D., Dalton, James T. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Nuclear Receptor Signaling Atlas
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602589/ https://www.ncbi.nlm.nih.gov/pubmed/19079612 http://dx.doi.org/10.1621/nrs.06010 |
Ejemplares similares
-
Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling
por: Narayanan, Ramesh, et al.
Publicado: (2014) -
An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer
por: Mohler, Michael L., et al.
Publicado: (2021) -
Androgen Receptor: A Complex Therapeutic Target for Breast Cancer
por: Narayanan, Ramesh, et al.
Publicado: (2016) -
Destroying the androgen receptor (AR)-potential strategy to treat advanced prostate cancer
por: Narayanan, Ramesh, et al.
Publicado: (2017) -
MicroRNAs Are Mediators of Androgen Action in Prostate and Muscle
por: Narayanan, Ramesh, et al.
Publicado: (2010)