Cargando…

Evaluating the safety of a rotavirus vaccine: the REST of the story

The Rotavirus Efficacy and Safety Trial (REST) was a blinded, placebo-controlled study of the live pentavalent human-bovine vaccine, RotaTeq® (Merck & Co. Inc., West Point, PA). REST was noteworthy because its primary objective was to evaluate the safety of RotaTeq® with regard to intussusceptio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heyse, Joseph F, Kuter, Barbara J, Dallas, Michael J, Heaton, Penny
Formato:	Texto
Lenguaje:	English
Publicado:	Sage 2008
Materias:	Design
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602609/ https://www.ncbi.nlm.nih.gov/pubmed/18375651 http://dx.doi.org/10.1177/1740774508090507

Ejemplares similares

Robustness of the healthcare utilization results from the Rotavirus Efficacy and Safety Trial (REST) evaluating the human-bovine (WC3) reassortant pentavalent rotavirus vaccine (RV5)
por: Itzler, Robbin, et al.
Publicado: (2010)

Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom
por: Török, M Estée, et al.
Publicado: (2021)

Using simulated infectious disease outbreaks to inform site selection and sample size for individually randomized vaccine trials during an ongoing epidemic
por: Madewell, Zachary J, et al.
Publicado: (2021)

EBOVAC-Salone: Lessons learned from implementing an Ebola vaccine trial in an Ebola-affected country
por: Mooney, Thomas, et al.
Publicado: (2018)

A platform trial design for preventive vaccines against Marburg virus and other emerging infectious disease threats
por: Longini, Ira M, et al.
Publicado: (2022)

Data on energy and economic evaluation and microbial assessment of anaerobic co-digestion of fruit rind of Telfairia occidentalis (Fluted pumpkin) and poultry manure
por: Dahunsi, S.O., et al.
Publicado: (2018)

A point-of-care clinical trial comparing insulin administered using a sliding scale versus a weight-based regimen
por: Fiore, Louis D, et al.
Publicado: (2011)

Design and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014–2015 outbreak
por: Edwards, Tansy, et al.
Publicado: (2016)

Design of the HPTN 065 (TLC-Plus) study: A study to evaluate the feasibility of an enhanced test, link-to-care, plus treat approach for HIV prevention in the United States
por: Gamble, Theresa, et al.
Publicado: (2017)

Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer
por: Demark-Wahnefried, Wendy, et al.
Publicado: (2008)

Rationale, challenges, and participants in a Phase II trial of a botanical product for chronic hepatitis C
por: Reddy, K Rajender, et al.
Publicado: (2012)

Extensional rheological data from ex-situ measurements for predicting porous media behaviour of the viscoelastic EOR polymers
por: Azad, M.S., et al.
Publicado: (2018)

The Rotavirus Vaccine Story: From Discovery to the Eventual Control of Rotavirus Disease
por: Glass, Roger I, et al.
Publicado: (2021)

Do Bayesian adaptive trials offer advantages for comparative effectiveness research? Protocol for the RE-ADAPT study
por: Connor, Jason T, et al.
Publicado: (2013)

Data on the Amphidinium carterae Dn241EHU isolation and morphological and molecular characterization
por: Seoane, S., et al.
Publicado: (2018)

Chromatin structure profile data from DNS-seq: Differential nuclease sensitivity mapping of four reference tissues of B73 maize (Zea mays L)
por: Turpin, Zachary M., et al.
Publicado: (2018)

Technical data of a grid-connected photovoltaic/wind hybrid system with and without storage battery for residential buildings located in a warm area
por: Baglivo, Cristina, et al.
Publicado: (2018)

Redesigning a large school-based clinical trial in response to changes in community practice
por: Gerald, Lynn B, et al.
Publicado: (2011)

Data set and model code on the optimal operating state of a negative emission polygeneration system
por: Aviso, Kathleen B., et al.
Publicado: (2020)

The optimal design of stepped wedge trials with equal allocation to sequences and a comparison to other trial designs
por: Thompson, Jennifer A, et al.
Publicado: (2017)

Designing a childhood obesity preventive intervention using the multiphase optimization strategy: The Healthy Bodies Project
por: Francis, Lori A, et al.
Publicado: (2023)

A data set on anthropometric measurements and degree of discomfort of physically disabled workers for ergonomic requirements in work space design
por: Mistarihi, Mahmoud Z.
Publicado: (2020)

Air temperature and mean radiant temperature data, collected and simulated across a radiantly-heated high-bay laboratory
por: Guo, Hongshan, et al.
Publicado: (2020)

Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer
por: Brown, Louise C, et al.
Publicado: (2022)

A spatial database of CO(2) emissions, urban form fragmentation and city-scale effect related impact factors for the low carbon urban system in Jinjiang city, China
por: Dai, Shaoqing, et al.
Publicado: (2020)

The FOsmetpantotenate Replacement Therapy (FORT) randomized, double-blind, Placebo-controlled pivotal trial: Study design and development methodology of a novel primary efficacy outcome in patients with pantothenate kinase-associated neurodegeneration
por: Klopstock, Thomas, et al.
Publicado: (2019)

Randomized trials of alcohol-use interventions with college students and their parents: lessons from the Transitions Project
por: Fernandez, AC, et al.
Publicado: (2011)

The development and description of the comparison group in the Look AHEAD trial
Publicado: (2011)

Statistical aspects of the TNK-S2B trial of tenecteplase versus alteplase in acute ischemic stroke: an efficient, dose-adaptive, seamless phase II/III design
por: Levin, Bruce, et al.
Publicado: (2011)

Data based investigation of the energy metering type, billing and usage of sampled residents of Ota Community in Nigeria
por: Adekitan, Aderibigbe Israel, et al.
Publicado: (2018)

Dataset for the estimation of costs for direct contact condenser
por: Liu, Dunyu, et al.
Publicado: (2018)

Data on safe hydrogen production from the solar photovoltaic solar panel through alkaline electrolyser under Algerian climate
por: Menad, Chawki Ameur, et al.
Publicado: (2018)

Data on combination of parabolic solar system with CH(4) cycle and power tower solar system with Cu–Cl cycle for hydrogen production in the city of Ghardaia (Algeria)
por: menad, Chawki Ameur, et al.
Publicado: (2018)

Spatial electricity market data for the power system of Kazakhstan
por: Assembayeva, Makpal, et al.
Publicado: (2019)

Data on the thermo-fluid simulation of open-cathode fuel cell stack depending on the location of the oxidizer/cooling supply system
por: Anisimov, Evgeny, et al.
Publicado: (2020)

Data on verbal expressions for thermal sensation and comfort in the Greek language
por: Pantavou, Katerina, et al.
Publicado: (2020)

Rotavirus Vaccines: a story of success with challenges ahead
por: O’Ryan, Miguel
Publicado: (2017)

The rationale, design, and methods of a randomized, controlled trial to evaluate the efficacy and safety of an active strategy for the diagnosis and treatment of acute pulmonary embolism during exacerbations of chronic obstructive pulmonary disease
por: Jiménez, David, et al.
Publicado: (2019)

Rationale and design of a study to assess the safety and efficacy of rNAPc2 in COVID-19: the Phase 2b ASPEN-COVID-19 trial
por: Hess, Connie N., et al.
Publicado: (2022)

Rationale and design of a randomized, double‐blind, event‐driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and significant coronary artery disease following an exacerbation of heart failure: the COMMANDER HF trial
por: Zannad, Faiez, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qku1hh1sb1p27gmqcmlfpcepdt