Cargando…

In vitro initial attachment of HIV-1 integrase to viral ends: control of the DNA specific interaction by the oligomerization state

HIV-1 integrase (IN) oligomerization and DNA recognition are crucial steps for the subsequent events of the integration reaction. Recent advances described the involvement of stable intermediary complexes including dimers and tetramers in the in vitro integration processes, but the initial attachmen...

Descripción completa

Detalles Bibliográficos
Autores principales: Lesbats, P., Métifiot, M., Calmels, C., Baranova, S., Nevinsky, G., Andreola, M. L., Parissi, V.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602759/
https://www.ncbi.nlm.nih.gov/pubmed/18987001
http://dx.doi.org/10.1093/nar/gkn796