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Properties of pseudo-complementary DNA substituted with weakly pairing analogs of guanine or cytosine

A straightforward enzymatic protocol for converting regular DNA into pseudo-complementary DNA could improve the performance of oligonucleotide microarrays by generating readily hybridizable structure-free targets. Here we screened several highly destabilizing analogs of G and C for one that could be...

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Detalles Bibliográficos
Autores principales:	Lahoud, Georges, Timoshchuk, Victor, Lebedev, Alexandre, Arar, Khalil, Hou, Ya-Ming, Gamper, Howard
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Chemistry and Synthetic Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602760/ https://www.ncbi.nlm.nih.gov/pubmed/18987000 http://dx.doi.org/10.1093/nar/gkn797

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