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Reciprocal regulation of glycine-rich RNA-binding proteins via an interlocked feedback loop coupling alternative splicing to nonsense-mediated decay in Arabidopsis

The Arabidopsis RNA-binding protein AtGRP8 undergoes negative autoregulation at the post-transcriptional level. An elevated AtGRP8 protein level promotes the use of a cryptic 5′ splice site to generate an alternatively spliced transcript, as_AtGRP8, retaining the 5′ half of the intron with a prematu...

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Detalles Bibliográficos
Autores principales: Schöning, Jan C., Streitner, Corinna, Meyer, Irmtraud M., Gao, Yahong, Staiger, Dorothee
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602770/
https://www.ncbi.nlm.nih.gov/pubmed/18987006
http://dx.doi.org/10.1093/nar/gkn847

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