IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production

Multiple sclerosis (MS) and type 1 diabetes (T1D) are organ-specific autoimmune disorders with significant heritability, part of which is conferred by shared alleles. For decades, the Human Leukocyte Antigen (HLA) complex was the only known susceptibility locus for both T1D and MS, but loci outside...

Descripción completa

Detalles Bibliográficos
Autores principales: Maier, Lisa M., Lowe, Christopher E., Cooper, Jason, Downes, Kate, Anderson, David E., Severson, Christopher, Clark, Pamela M., Healy, Brian, Walker, Neil, Aubin, Cristin, Oksenberg, Jorge R., Hauser, Stephen L., Compston, Alistair, Sawcer, Stephen, De Jager, Philip L., Wicker, Linda S., Todd, John A., Hafler, David A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602853/
https://www.ncbi.nlm.nih.gov/pubmed/19119414
http://dx.doi.org/10.1371/journal.pgen.1000322

Ejemplares similares

Ejemplares similares