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Porphyrin Homeostasis Maintained by ABCG2 Regulates Self-Renewal of Embryonic Stem Cells

BACKGROUND: Under appropriate culture conditions, undifferentiated embryonic stem (ES) cells can undergo multiple self-renewal cycles without loss of pluripotency suggesting they must be equipped with specific defense mechanisms to ensure sufficient genetic stability during self-renewal expansion. T...

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Detalles Bibliográficos
Autores principales: Susanto, Jimmy, Lin, Yu-Hsing, Chen, Yun-Nan, Shen, Chia-Rui, Yan, Yu-Ting, Tsai, Sheng-Ta, Chen, Chung-Hsuan, Shen, Chia-Ning
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602981/
https://www.ncbi.nlm.nih.gov/pubmed/19107196
http://dx.doi.org/10.1371/journal.pone.0004023