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Myocardial Hypertrophy Overrides the Angiogenic Response to Hypoxia

BACKGROUND: Cyanosis and myocardial hypertrophy frequently occur in combination. Hypoxia or cyanosis can be potent inducers of angiogenesis, regulating the expression of hypoxia-inducible factors (HIF), vascular endothelial growth factors (VEGF), and VEGF receptors (VEGFR-1 and 2); in contrast, pres...

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Detalles Bibliográficos
Autores principales: Choi, Yeong-Hoon, Cowan, Douglas B., Nathan, Meena, Poutias, Dimitrios, Stamm, Christof, del Nido, Pedro J., McGowan, Francis X.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603310/
https://www.ncbi.nlm.nih.gov/pubmed/19112498
http://dx.doi.org/10.1371/journal.pone.0004042