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Reduction of Orc6 Expression Sensitizes Human Colon Cancer Cells to 5-Fluorouracil and Cisplatin

Previous studies from our group have shown that the expression levels of Orc6 were highly elevated in colorectal cancer patient specimens and the induction of Orc6 was associated with 5-fluorouracil (5-FU) treatment. The goal of this study was to investigate the molecular and cellular impact of Orc6...

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Detalles Bibliográficos
Autores principales: Gavin, Elaine J., Song, Bo, Wang, Yuan, Xi, Yaguang, Ju, Jingfang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603583/
https://www.ncbi.nlm.nih.gov/pubmed/19112505
http://dx.doi.org/10.1371/journal.pone.0004054