Cargando…

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

Intranasal delivery provides a practical, non-invasive method of bypassing the blood-brain barrier (BBB) to deliver therapeutic agents to the brain and spinal cord. This technology allows drugs that do not cross the BBB to be delivered to the central nervous system within minutes. It also directly d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hanson, Leah R, Frey, William H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604883/ https://www.ncbi.nlm.nih.gov/pubmed/19091002 http://dx.doi.org/10.1186/1471-2202-9-S3-S5

Ejemplares similares

Mechanisms of Intranasal Deferoxamine in Neurodegenerative and Neurovascular Disease
por: Kosyakovsky, Jacob, et al.
Publicado: (2021)

Advances and Challenges in Intranasal Delivery of Antipsychotic Agents Targeting the Central Nervous System
por: Pandey, Manisha, et al.
Publicado: (2022)

Intranasal administration of elastin-like polypeptide for therapeutic delivery to the central nervous system
por: McGowan, Jeremy WD, et al.
Publicado: (2016)

Intranasal Treatment of Central Nervous System Dysfunction in Humans
por: Chapman, Colin D., et al.
Publicado: (2012)

Evaluation of Recent Intranasal Drug Delivery Systems to the Central Nervous System
por: Crowe, Tyler P., et al.
Publicado: (2022)

Editorial: Intranasal Delivery of Central Nervous System Active Drugs: Opportunities and Challenges
por: Rodrigues, Márcio, et al.
Publicado: (2022)

Delivery of Therapeutic Agents to the Central Nervous System and the Promise of Extracellular Vesicles
por: René, Charlotte A., et al.
Publicado: (2021)

Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability
por: Zhang, Qun-Lin, et al.
Publicado: (2017)

Intranasal Delivery of Nerve Growth Factor in Neurodegenerative Diseases and Neurotrauma
por: Manni, Luigi, et al.
Publicado: (2021)

Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System
por: Flamm, Johannes, et al.
Publicado: (2022)

Application progress of RVG peptides to facilitate the delivery of therapeutic agents into the central nervous system
por: Wang, Qinghua, et al.
Publicado: (2021)

Pathways for Small Molecule Delivery to the Central Nervous System Across the Blood-Brain Barrier
por: Mikitsh, John L, et al.
Publicado: (2014)

Optimizing Absorption for Intranasal Delivery of Drugs Targeting the Central Nervous System Using Alkylsaccharide Permeation Enhancers
por: Madden, Stuart, et al.
Publicado: (2023)

Central nervous system uptake of intranasal glutathione in Parkinson’s disease
por: Mischley, Laurie K, et al.
Publicado: (2016)

Recent progress in the intranasal PLGA-based drug delivery for neurodegenerative diseases treatment
por: Aghaei Delche, Nasim, et al.
Publicado: (2023)

Intranasal delivery of full-length anti-Nogo-A antibody: A potential alternative route for therapeutic antibodies to central nervous system targets
por: Correa, Daphne, et al.
Publicado: (2023)

Multiple Sclerosis and the Blood-Central Nervous System Barrier
por: Palmer, Alan M.
Publicado: (2013)

Microphysiological Systems for Neurodegenerative Diseases in Central Nervous System
por: Bae, Mihyeon, et al.
Publicado: (2020)

Immunomodulation induced by central nervous system‐related peptides as a therapeutic strategy for neurodegenerative disorders
por: Palumbo, María Laura, et al.
Publicado: (2021)

Intranasal nerve growth factor bypasses the blood-brain barrier and affects spinal cord neurons in spinal cord injury
por: Aloe, Luigi, et al.
Publicado: (2014)

Current State and Future Directions of Intranasal Delivery Route for Central Nervous System Disorders: A Scientometric and Visualization Analysis
por: Wu, Haiyang, et al.
Publicado: (2021)

ABC efflux transporters at blood-central nervous system barriers and their implications for treating spinal cord disorders
por: Koehn, Liam M.
Publicado: (2020)

Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke
por: Brzica, Hrvoje, et al.
Publicado: (2017)

VHHs as tools for therapeutic protein delivery to the central nervous system
por: Wouters, Yessica, et al.
Publicado: (2022)

Bypassing the Blood–Brain Barrier: Direct Intracranial Drug Delivery in Epilepsies
por: Gernert, Manuela, et al.
Publicado: (2020)

Intranasal Delivery of Genistein-Loaded Nanoparticles as a Potential Preventive System against Neurodegenerative Disorders
por: Rassu, Giovanna, et al.
Publicado: (2018)

Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases
por: Su, Yu, et al.
Publicado: (2020)

The Route by Which Intranasally Delivered Stem Cells Enter the Central Nervous System
por: Galeano, Carlos, et al.
Publicado: (2018)

Advances in intranasal application of stem cells in the treatment of central nervous system diseases
por: Zhang, Yu-Ting, et al.
Publicado: (2021)

Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases
por: Tian, Yang, et al.
Publicado: (2021)

Breaking Barriers: Bioinspired Strategies for Targeted Neuronal Delivery to the Central Nervous System
por: Spencer, Ana P., et al.
Publicado: (2020)

Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration
por: Soleimanizadeh, Arghavan, et al.
Publicado: (2021)

New idea to promote the clinical applications of stem cells or their extracellular vesicles in central nervous system disorders: Combining with intranasal delivery
por: Li, Yaosheng, et al.
Publicado: (2022)

Characterization of the blood brain barrier in pediatric central nervous system neoplasms
por: Hong, Christopher S., et al.
Publicado: (2016)

Role of the Blood-Brain Barrier in Central Nervous System Insulin Resistance
por: Rhea, Elizabeth M., et al.
Publicado: (2019)

Central Nervous System (CNS) Delivery of Glucocorticoids Is Fine-Tuned by Saturable Transporters at the Blood-CNS Barriers and Nonbarrier Regions
por: Mason, Brittany L., et al.
Publicado: (2010)

Intranasal Insulin Ameliorates Experimental Diabetic Neuropathy
por: Francis, George, et al.
Publicado: (2009)

Deoxyribozymes: New Therapeutics to Treat Central Nervous System Disorders
por: Grimpe, Barbara
Publicado: (2011)

Nanotherapeutics for Nose-to-Brain Drug Delivery: An Approach to Bypass the Blood Brain Barrier
por: Lee, David, et al.
Publicado: (2021)

Novel Therapeutic Delivery of Nanocurcumin in Central Nervous System Related Disorders
por: Panzarini, Elisa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1olcfvisn21nldp690jpc25thr