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Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase
The peptides angiotensin IV and LVV-hemorphin 7 were found to enhance memory in a number of memory tasks and reverse the performance deficits in animals with experimentally induced memory loss. These peptides bound specifically to the enzyme insulin-regulated aminopeptidase (IRAP), which is proposed...
Autores principales: | Chai, Siew Yeen, Yeatman, Holly R, Parker, Michael W, Ascher, David B, Thompson, Philip E, Mulvey, Hayley T, Albiston, Anthony L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604898/ https://www.ncbi.nlm.nih.gov/pubmed/19090987 http://dx.doi.org/10.1186/1471-2202-9-S2-S14 |
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