Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

2-Arachidonoylglycerol (2-AG) and anandamide are endocannabinoids that activate cannabinoid receptors CB1 and CB2. Endocannabinoid signaling is terminated by enzymatic hydrolysis, a process that, for anandamide, is mediated by fatty acid amide hydrolase (FAAH) and, for 2-AG, is thought to involve mo...

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Detalles Bibliográficos
Autores principales: Long, Jonathan Z., Li, Weiwei, Booker, Lamont, Burston, James J., Kinsey, Steven G., Schlosburg, Joel E., Pavón, Franciso J., Serrano, Antonia M., Selley, Dana E., Parsons, Loren H., Lichtman, Aron H., Cravatt, Benjamin F.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605181/
https://www.ncbi.nlm.nih.gov/pubmed/19029917
http://dx.doi.org/10.1038/nchembio.129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605181/
https://www.ncbi.nlm.nih.gov/pubmed/19029917
http://dx.doi.org/10.1038/nchembio.129

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