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The replisome uses mRNA as a primer after colliding with RNA polymerase

Replication forks are impeded by DNA damage and protein-nucleic acid complexes such as transcribing RNA polymerase. For example, head-on collision of the replisome with RNA polymerase results in replication fork arrest. However, co-directional collision of the replisome with RNA polymerase has littl...

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Detalles Bibliográficos
Autores principales: Pomerantz, Richard T., O’Donnell, Mike
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605185/
https://www.ncbi.nlm.nih.gov/pubmed/19020502
http://dx.doi.org/10.1038/nature07527