Cargando…
The replisome uses mRNA as a primer after colliding with RNA polymerase
Replication forks are impeded by DNA damage and protein-nucleic acid complexes such as transcribing RNA polymerase. For example, head-on collision of the replisome with RNA polymerase results in replication fork arrest. However, co-directional collision of the replisome with RNA polymerase has littl...
Autores principales: | Pomerantz, Richard T., O’Donnell, Mike |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605185/ https://www.ncbi.nlm.nih.gov/pubmed/19020502 http://dx.doi.org/10.1038/nature07527 |
Ejemplares similares
-
Reconstitution of a eukaryotic replisome reveals the mechanism of asymmetric distribution of DNA polymerases
por: Yurieva, Olga, et al.
Publicado: (2016) -
Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
por: Pomerantz, Richard T., et al.
Publicado: (2010) -
Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome
por: Yuan, Zuanning, et al.
Publicado: (2020) -
The eukaryotic CMG helicase pumpjack and integration into the replisome
por: Sun, Jingchuan, et al.
Publicado: (2016) -
Primer‐dependent Amplification of mdr1 mRNA by Polymerase Chain Reaction
por: Sugawara, Isamu, et al.
Publicado: (1992)