Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus

Although the importance of cytotoxic T lymphocytes and neutralizing antibodies for antiviral defense is well known, the antiviral mechanism of Th1 remains unclear. We show that Th1 cells mediate noncytolytic antiviral protection independent of direct lysis through local secretion of IFN-γ after herp...

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Detalles Bibliográficos
Autores principales: Iijima, Norifumi, Linehan, Melissa M., Zamora, Melodie, Butkus, Debbie, Dunn, Robert, Kehry, Marilyn R., Laufer, Terri M., Iwasaki, Akiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605233/
https://www.ncbi.nlm.nih.gov/pubmed/19047439
http://dx.doi.org/10.1084/jem.20082039

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