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RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes

Continued antibody gene rearrangement, termed receptor editing, is an important mechanism of central B cell tolerance that may be defective in some autoimmune individuals. We describe a quantitative assay for recombining sequence (RS) rearrangement that we use to estimate levels of antibody light ch...

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Detalles Bibliográficos
Autores principales:	Panigrahi, Anil K., Goodman, Noah G., Eisenberg, Robert A., Rickels, Michael R., Naji, Ali, Luning Prak, Eline T.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605238/ https://www.ncbi.nlm.nih.gov/pubmed/19075293 http://dx.doi.org/10.1084/jem.20082053

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