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Solving the Puzzle of Chronic Ischemic Mitral Regurgitation

Chronic ischemic mitral regurgitation is a prevalent problem among patients following a myocardial infarction. Until recently, the pathophysiology was poorly understood, resulting in surgical strategies with suboptimal results and limited durability. The surgical approach has evolved from revascular...

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Detalles Bibliográficos
Autores principales: Hashim, Sabet W., Rousou, Anthony J., Geirsson, Arnar, Ragnarsson, Sigurdur
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605311/
https://www.ncbi.nlm.nih.gov/pubmed/19099047
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author Hashim, Sabet W.
Rousou, Anthony J.
Geirsson, Arnar
Ragnarsson, Sigurdur
author_facet Hashim, Sabet W.
Rousou, Anthony J.
Geirsson, Arnar
Ragnarsson, Sigurdur
author_sort Hashim, Sabet W.
collection PubMed
description Chronic ischemic mitral regurgitation is a prevalent problem among patients following a myocardial infarction. Until recently, the pathophysiology was poorly understood, resulting in surgical strategies with suboptimal results and limited durability. The surgical approach has evolved from revascularization alone to an additional mitral valve procedure, replacement, or repair. When the valve was repaired, isolated annuloplasty was performed. The dilemma that surgeons had when repairing a mitral valve was which type of ring to use and what size. In all series with annuloplasty alone, the results were poor with very high recurrence rates. The primary feature of ischemic mitral regurgitation is a prolapse of the anterior leaflet at A3 ± A2. This prolapse can be caused by fibrotic elongation of the papillary muscle supporting A3 ± A2 or tethering of P3 by a ballooning posterior left ventricular wall. Using a technique that corrects this prolapse with Gore-Tex neochords, we have achieved excellent results with effective and durable correction of the ischemic mitral regurgitation.
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spelling pubmed-26053112008-12-19 Solving the Puzzle of Chronic Ischemic Mitral Regurgitation Hashim, Sabet W. Rousou, Anthony J. Geirsson, Arnar Ragnarsson, Sigurdur Yale J Biol Med Review Chronic ischemic mitral regurgitation is a prevalent problem among patients following a myocardial infarction. Until recently, the pathophysiology was poorly understood, resulting in surgical strategies with suboptimal results and limited durability. The surgical approach has evolved from revascularization alone to an additional mitral valve procedure, replacement, or repair. When the valve was repaired, isolated annuloplasty was performed. The dilemma that surgeons had when repairing a mitral valve was which type of ring to use and what size. In all series with annuloplasty alone, the results were poor with very high recurrence rates. The primary feature of ischemic mitral regurgitation is a prolapse of the anterior leaflet at A3 ± A2. This prolapse can be caused by fibrotic elongation of the papillary muscle supporting A3 ± A2 or tethering of P3 by a ballooning posterior left ventricular wall. Using a technique that corrects this prolapse with Gore-Tex neochords, we have achieved excellent results with effective and durable correction of the ischemic mitral regurgitation. Yale Journal of Biology and Medicine 2008-12 2008-12 /pmc/articles/PMC2605311/ /pubmed/19099047 Text en Copyright ©2008, Yale Journal of Biology and Medicine https://creativecommons.org/licenses/by-nc/3.0/ This is an open access article distributed under the terms of the Creative Commons CC BY-NC license, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use the material for commercial purposes.
spellingShingle Review
Hashim, Sabet W.
Rousou, Anthony J.
Geirsson, Arnar
Ragnarsson, Sigurdur
Solving the Puzzle of Chronic Ischemic Mitral Regurgitation
title Solving the Puzzle of Chronic Ischemic Mitral Regurgitation
title_full Solving the Puzzle of Chronic Ischemic Mitral Regurgitation
title_fullStr Solving the Puzzle of Chronic Ischemic Mitral Regurgitation
title_full_unstemmed Solving the Puzzle of Chronic Ischemic Mitral Regurgitation
title_short Solving the Puzzle of Chronic Ischemic Mitral Regurgitation
title_sort solving the puzzle of chronic ischemic mitral regurgitation
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605311/
https://www.ncbi.nlm.nih.gov/pubmed/19099047
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