Transient antiretroviral therapy selecting for common HIV-1 mutations substantially accelerates the appearance of rare mutations

BACKGROUND: Highly selective antiretroviral (ARV) regimens such as single dose nevirapine (NVP) used for prevention of mother to child transmission (PMTCT) in resource-limited settings produce transient increases in otherwise marginal subpopulations of cells infected by mutant genomes. The longer te...

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Detalles Bibliográficos
Autores principales: Shiri, Tinevimbo, Welte, Alex
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605440/
https://www.ncbi.nlm.nih.gov/pubmed/19014593
http://dx.doi.org/10.1186/1742-4682-5-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605440/
https://www.ncbi.nlm.nih.gov/pubmed/19014593
http://dx.doi.org/10.1186/1742-4682-5-25

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