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Transient antiretroviral therapy selecting for common HIV-1 mutations substantially accelerates the appearance of rare mutations
BACKGROUND: Highly selective antiretroviral (ARV) regimens such as single dose nevirapine (NVP) used for prevention of mother to child transmission (PMTCT) in resource-limited settings produce transient increases in otherwise marginal subpopulations of cells infected by mutant genomes. The longer te...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605440/ https://www.ncbi.nlm.nih.gov/pubmed/19014593 http://dx.doi.org/10.1186/1742-4682-5-25 |