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The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid
BACKGROUND: Transarterial Chemoembolization (TACE) has been recognized as a successful way of managing symptomatic and/or progressive hepatic carcinoid metastases not amenable to surgical resection. Although it is a fairly safe procedure, it is not without its complications. CASE PRESENTATION: This...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605455/ https://www.ncbi.nlm.nih.gov/pubmed/19032771 http://dx.doi.org/10.1186/1477-7819-6-125 |
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author | Pearson, Andrew C Steinberg, Steven Shah, Manisha H Bloomston, Mark |
author_facet | Pearson, Andrew C Steinberg, Steven Shah, Manisha H Bloomston, Mark |
author_sort | Pearson, Andrew C |
collection | PubMed |
description | BACKGROUND: Transarterial Chemoembolization (TACE) has been recognized as a successful way of managing symptomatic and/or progressive hepatic carcinoid metastases not amenable to surgical resection. Although it is a fairly safe procedure, it is not without its complications. CASE PRESENTATION: This is a case of a 53 year-old woman with a patent foramen ovale (PFO) and mild pulmonary hypertension who underwent TACE for progressive carcinoid liver metastases. She developed acute heart failure, due to a severe inflammatory response; this resulted in pneumatosis intestinalis due to non-occlusive mesenteric ischemia. We describe the successful non-operative management of her pneumatosis intestinalis and the role of a PFO in this patient's heart failure. CONCLUSION: TACE remains an effective and safe treatment for metastatic carcinoid not amenable to resection, this case illustrates the complexity of complications that can arise. A multi-disciplinary approach including ready access to advanced critical care facilities is recommended in managing such complex patients. |
format | Text |
id | pubmed-2605455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26054552008-12-19 The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid Pearson, Andrew C Steinberg, Steven Shah, Manisha H Bloomston, Mark World J Surg Oncol Case Report BACKGROUND: Transarterial Chemoembolization (TACE) has been recognized as a successful way of managing symptomatic and/or progressive hepatic carcinoid metastases not amenable to surgical resection. Although it is a fairly safe procedure, it is not without its complications. CASE PRESENTATION: This is a case of a 53 year-old woman with a patent foramen ovale (PFO) and mild pulmonary hypertension who underwent TACE for progressive carcinoid liver metastases. She developed acute heart failure, due to a severe inflammatory response; this resulted in pneumatosis intestinalis due to non-occlusive mesenteric ischemia. We describe the successful non-operative management of her pneumatosis intestinalis and the role of a PFO in this patient's heart failure. CONCLUSION: TACE remains an effective and safe treatment for metastatic carcinoid not amenable to resection, this case illustrates the complexity of complications that can arise. A multi-disciplinary approach including ready access to advanced critical care facilities is recommended in managing such complex patients. BioMed Central 2008-11-25 /pmc/articles/PMC2605455/ /pubmed/19032771 http://dx.doi.org/10.1186/1477-7819-6-125 Text en Copyright © 2008 Pearson et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Pearson, Andrew C Steinberg, Steven Shah, Manisha H Bloomston, Mark The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid |
title | The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid |
title_full | The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid |
title_fullStr | The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid |
title_full_unstemmed | The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid |
title_short | The complicated management of a patient following transarterial chemoembolization for metastatic carcinoid |
title_sort | complicated management of a patient following transarterial chemoembolization for metastatic carcinoid |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605455/ https://www.ncbi.nlm.nih.gov/pubmed/19032771 http://dx.doi.org/10.1186/1477-7819-6-125 |
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