Cargando…

ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

BACKGROUND: Aldehyde dehydrogenase isozymes ALDH1A1 and ALDH3A1 are highly expressed in non small cell lung cancer. Neither the mechanisms nor the biologic significance for such over expression have been studied. METHODS: We have employed oligonucleotide microarrays to analyze changes in gene profil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moreb, Jan S, Baker, Henry V, Chang, Lung-Ji, Amaya, Maria, Lopez, M Cecilia, Ostmark, Blanca, Chou, Wayne
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605459/ https://www.ncbi.nlm.nih.gov/pubmed/19025616 http://dx.doi.org/10.1186/1476-4598-7-87

Ejemplares similares

Determination of Aldehyde Dehydrogenase (ALDH) Isozymes in Human Cancer Samples - Comparison of Kinetic and Immunochemical Assays
por: Wroczynski, Piotr, et al.
Publicado: (2002)

Ubiquitin carboxyl-terminal hydrolase isozyme L5 inhibits human glioma cell migration and invasion via downregulating SNRPF
por: Ge, Jiafeng, et al.
Publicado: (2017)

Downregulation of LOC441461 Promotes Cell Growth and Motility in Human Gastric Cancer
por: Lee, Sang-soo, et al.
Publicado: (2022)

ALDH1L1 Inhibits Cell Motility Via Dephosphorylation of Cofilin by PP1 and PP2A
por: Oleinik, Natalia V., et al.
Publicado: (2010)

Effects of L-carnitine and Pentoxifylline on the Activity of Lactate Dehydrogenase C(4) isozyme and Motility of Testicular Spermatozoa in Mice
por: Aliabadi, Elham, et al.
Publicado: (2013)

ALDH1A2 suppresses epithelial ovarian cancer cell proliferation and migration by downregulating STAT3
por: Wang, Yichen, et al.
Publicado: (2018)

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH(High) Melanoma-Initiating Cells
por: Sarvi, Sana, et al.
Publicado: (2018)

Male Mice Express Spermatogenic Cell-Specific Triosephosphate Isomerase Isozymes
por: Ijiri, Takashi W, et al.
Publicado: (2013)

The rarity of ALDH (+) cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients
por: Hoang, Van T., et al.
Publicado: (2015)

Deletion and downregulation of MTAP contribute to the motility of esophageal squamous carcinoma cells
por: Cheng, Xiao-Yu, et al.
Publicado: (2017)

MicroRNA-204 Inhibits the Growth and Motility of Colorectal Cancer Cells by Downregulation of CXCL8
por: Shuai, Feng, et al.
Publicado: (2018)

A Cascade of Protein Kinase C Isozymes Promotes Cytoskeletal Polarization in T Cells
por: Quann, Emily J., et al.
Publicado: (2011)

Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility
por: Stavik, Benedicte, et al.
Publicado: (2011)

Cell Motility and Cancer
por: De la Fuente, Ildefonso M., et al.
Publicado: (2020)

Na,K-ATPase Isozymes in Colorectal Cancer and Liver Metastases
por: Baker Bechmann, Marc, et al.
Publicado: (2016)

Selective inhibition of sterolO-acyltransferase 1 isozyme by beauveriolide III in intact cells
por: Ohshiro, Taichi, et al.
Publicado: (2017)

Hereditary pituitary dwarfism in mice affects skeletal and cardiac myosin isozyme transitions differently
Publicado: (1985)

Evaluation of STAT3 Signaling in ALDH+ and ALDH+/CD44+/CD24− Subpopulations of Breast Cancer Cells
por: Lin, Li, et al.
Publicado: (2013)

Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1
por: Abdelbaset-Ismail, A, et al.
Publicado: (2017)

The Role of DUOX Isozymes in the Respiratory Tract Epithelium
por: Harper, Richard
Publicado: (2008)

Kynurenine Aminotransferase Isozyme Inhibitors: A Review
por: Nematollahi, Alireza, et al.
Publicado: (2016)

Characterizing Isozymes of Chlorite Dismutase for Water Treatment
por: Mobilia, Kellen C., et al.
Publicado: (2017)

TGF-β-induced cell motility requires downregulation of ARHGAPs to sustain Rac1 activity
por: Motizuki, Mitsuyoshi, et al.
Publicado: (2021)

Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility
por: Gajendran, Nithya, et al.
Publicado: (2023)

PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations
por: Świerczewska, Monika, et al.
Publicado: (2019)

Galiellalactone Inhibits Stem Cell-Like ALDH-Positive Prostate Cancer Cells
por: Hellsten, Rebecka, et al.
Publicado: (2011)

Cell Motility
por: Lenz, Peter
Publicado: (2008)

Downregulation of HMGB1 in thymoma cells affects T cell differentiation
por: Li, Jian, et al.
Publicado: (2023)

Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells
por: Gehlot, Prashasnika, et al.
Publicado: (2016)

Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis
por: Topping, Traci, et al.
Publicado: (2022)

ALDH1-Mediated Autophagy Sensitizes Glioblastoma Cells to Ferroptosis
por: Wu, Yang, et al.
Publicado: (2022)

ALDH1-High Ovarian Cancer Stem-Like Cells Can Be Isolated from Serous and Clear Cell Adenocarcinoma Cells, and ALDH1 High Expression Is Associated with Poor Prognosis
por: Kuroda, Takafumi, et al.
Publicado: (2013)

Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ
Publicado: (1994)

Role of phosphodiesterase and adenylate cyclase isozymes in murine colonic glucagon-like peptide 1 secreting cells
por: Friedlander, Ronn S, et al.
Publicado: (2011)

An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins
por: Gada, Kirin D., et al.
Publicado: (2022)

FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7
por: Wang, Zeran, et al.
Publicado: (2013)

Lactobacilli Downregulate Transcription Factors in Helicobacter pylori That Affect Motility, Acid Tolerance and Antimicrobial Peptide Survival
por: Zuo, Fanglei, et al.
Publicado: (2022)

Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells
por: Liu, Xinwei, et al.
Publicado: (2016)

THE ULTRASTRUCTURAL LOCALIZATION OF THE ISOZYMES OF ASPARTATE AMINOTRANSFERASE IN MURINE TISSUES
por: Papadimitriou, J. M., et al.
Publicado: (1970)

Acetate Kinase Isozymes Confer Robustness in Acetate Metabolism
por: Chan, Siu Hung Joshua, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4jcbho0jg5ti4bl9759enro926