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FGF9-induced proliferative response to eosinophilic inflammation in oesophagitis

BACKGROUND: Oesophagitis is characterised by basal cell hyperplasia and activated eosinophils, which release mediators including major basic protein (MBP). MBP and its mimetic polyarginine activate the calcium sensing receptor (CaSR) on oesophageal epithelium. Fibroblast growth factor 9 (FGF9) is im...

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Detalles Bibliográficos
Autores principales: Mulder, D J, Pacheco, I, Hurlbut, D J, Mak, N, Furuta, G T, MacLeod, R J, Justinich, C J
Formato: Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605569/
https://www.ncbi.nlm.nih.gov/pubmed/18978176
http://dx.doi.org/10.1136/gut.2008.157628