Cargando…
One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds
In this work an efficient one-pot synthesis of substituted pyrroles 7a–n is described, which involves the in situ formation of dihydrofurans ethyl 5-butoxy-2-methyl-4,5-dihydrofuran-3-carboxylate (4), 1-(5-butoxy-2-methyl-4,5-dihydrofuran-3-yl)ethanone (5) and 5-butoxy-4,5-dihydrofuran-3-carbaldehyd...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605617/ https://www.ncbi.nlm.nih.gov/pubmed/19104671 http://dx.doi.org/10.3762/bjoc.4.45 |
| _version_ | 1782162868327677952 |
|---|---|
| author | da Silva, Fernando de C Fonseca, Mauricio G Rianelli, Renata de S Cunha, Anna C de Souza, Maria C B V Ferreira, Vitor F |
| author_facet | da Silva, Fernando de C Fonseca, Mauricio G Rianelli, Renata de S Cunha, Anna C de Souza, Maria C B V Ferreira, Vitor F |
| author_sort | da Silva, Fernando de C |
| collection | PubMed |
| description | In this work an efficient one-pot synthesis of substituted pyrroles 7a–n is described, which involves the in situ formation of dihydrofurans ethyl 5-butoxy-2-methyl-4,5-dihydrofuran-3-carboxylate (4), 1-(5-butoxy-2-methyl-4,5-dihydrofuran-3-yl)ethanone (5) and 5-butoxy-4,5-dihydrofuran-3-carbaldehyde (6) followed by reaction with primary amines. |
| format | Text |
| id | pubmed-2605617 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2008 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-26056172008-12-22 One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds da Silva, Fernando de C Fonseca, Mauricio G Rianelli, Renata de S Cunha, Anna C de Souza, Maria C B V Ferreira, Vitor F Beilstein J Org Chem Full Research Paper In this work an efficient one-pot synthesis of substituted pyrroles 7a–n is described, which involves the in situ formation of dihydrofurans ethyl 5-butoxy-2-methyl-4,5-dihydrofuran-3-carboxylate (4), 1-(5-butoxy-2-methyl-4,5-dihydrofuran-3-yl)ethanone (5) and 5-butoxy-4,5-dihydrofuran-3-carbaldehyde (6) followed by reaction with primary amines. Beilstein-Institut 2008-11-28 /pmc/articles/PMC2605617/ /pubmed/19104671 http://dx.doi.org/10.3762/bjoc.4.45 Text en Copyright © 2008, da Silva et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper da Silva, Fernando de C Fonseca, Mauricio G Rianelli, Renata de S Cunha, Anna C de Souza, Maria C B V Ferreira, Vitor F One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds |
| title | One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds |
| title_full | One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds |
| title_fullStr | One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds |
| title_full_unstemmed | One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds |
| title_short | One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds |
| title_sort | one-pot preparation of substituted pyrroles from α-diazocarbonyl compounds |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605617/ https://www.ncbi.nlm.nih.gov/pubmed/19104671 http://dx.doi.org/10.3762/bjoc.4.45 |
| work_keys_str_mv | AT dasilvafernandodec onepotpreparationofsubstitutedpyrrolesfromadiazocarbonylcompounds AT fonsecamauriciog onepotpreparationofsubstitutedpyrrolesfromadiazocarbonylcompounds AT rianellirenatades onepotpreparationofsubstitutedpyrrolesfromadiazocarbonylcompounds AT cunhaannac onepotpreparationofsubstitutedpyrrolesfromadiazocarbonylcompounds AT desouzamariacbv onepotpreparationofsubstitutedpyrrolesfromadiazocarbonylcompounds AT ferreiravitorf onepotpreparationofsubstitutedpyrrolesfromadiazocarbonylcompounds |