Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster

BACKGROUND: Clostridial neurotoxins (CNTs) are the most deadly toxins known and causal agents of botulism and tetanus neuroparalytic diseases. Despite considerable progress in understanding CNT structure and function, the evolutionary origins of CNTs remain a mystery as they are unique to Clostridiu...

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Detalles Bibliográficos
Autores principales: Doxey, Andrew C, Lynch, Michael DJ, Müller, Kirsten M, Meiering, Elizabeth M, McConkey, Brendan J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605760/
https://www.ncbi.nlm.nih.gov/pubmed/19014598
http://dx.doi.org/10.1186/1471-2148-8-316

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