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HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase

Human T-cell leukemia virus type-1 is the causative agent for adult T-cell leukemia. Previous research has established that the viral oncoprotein Tax mediates the transformation process by impairing cell cycle control and cellular response to DNA damage. We showed previously that Tax sequesters huCh...

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Detalles Bibliográficos
Autores principales:	Durkin, Sarah S., Guo, Xin, Fryrear, Kimberly A., Mihaylova, Valia T., Gupta, Saurabh K., Belgnaoui, S. Mehdi, Haoudi, Abdelali, Kupfer, Gary M., Semmes, O. John
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605996/ https://www.ncbi.nlm.nih.gov/pubmed/18957425 http://dx.doi.org/10.1074/jbc.M804931200

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