Cargando…

HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase

Human T-cell leukemia virus type-1 is the causative agent for adult T-cell leukemia. Previous research has established that the viral oncoprotein Tax mediates the transformation process by impairing cell cycle control and cellular response to DNA damage. We showed previously that Tax sequesters huCh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Durkin, Sarah S., Guo, Xin, Fryrear, Kimberly A., Mihaylova, Valia T., Gupta, Saurabh K., Belgnaoui, S. Mehdi, Haoudi, Abdelali, Kupfer, Gary M., Semmes, O. John
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605996/ https://www.ncbi.nlm.nih.gov/pubmed/18957425 http://dx.doi.org/10.1074/jbc.M804931200

Ejemplares similares

The Human Oxidative DNA Glycosylase NEIL1 Excises Psoralen-induced Interstrand DNA Cross-links in a Three-stranded DNA Structure
por: Couvé, Sophie, et al.
Publicado: (2009)

Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex
por: Hammel, Michal, et al.
Publicado: (2010)

Native R-loops Persist throughout the Mouse Mitochondrial DNA Genome
por: Brown, Timothy A., et al.
Publicado: (2008)

FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures
por: Yuan, Fenghua, et al.
Publicado: (2009)

hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response
por: Li, Yongjiang, et al.
Publicado: (2009)

Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
por: Huertas, Pablo, et al.
Publicado: (2009)

Human Heart Mitochondrial DNA Is Organized in Complex Catenated Networks Containing Abundant Four-way Junctions and Replication Forks
por: Pohjoismäki, Jaakko L. O., et al.
Publicado: (2009)

Mitotic Functions for SNAP45, a Subunit of the Small Nuclear RNA-activating Protein Complex SNAP(c)
por: Shanmugam, Mayilvahanan, et al.
Publicado: (2008)

A Thermodynamic Model for Nap1-Histone Interactions
por: Andrews, Andrew J., et al.
Publicado: (2008)

Cooperativity of Mus81·Mms4 with Rad54 in the Resolution of Recombination and Replication Intermediates
por: Matulova, Petra, et al.
Publicado: (2009)

Functions of MutLα, Replication Protein A (RPA), and HMGB1 in 5′-Directed Mismatch Repair
por: Genschel, Jochen, et al.
Publicado: (2009)

Crystal Structure of Malaria Parasite Nucleosome Assembly Protein: DISTINCT MODES OF PROTEIN LOCALIZATION AND HISTONE RECOGNITION
por: Gill, Jasmita, et al.
Publicado: (2009)

Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro
por: Pluciennik, Anna, et al.
Publicado: (2009)

The Viral Oncoprotein Tax Sequesters DNA Damage Response Factors by Tethering MDC1 to Chromatin
por: Belgnaoui, S. Mehdi, et al.
Publicado: (2010)

The SUMO-targeted ubiquitin ligase RNF4 regulates localization and function of the HTLV-1 oncoprotein Tax
por: Fryrear, Kimberly A, et al.
Publicado: (2011)

UV Damage in DNA Promotes Nucleosome Unwrapping
por: Duan, Ming-Rui, et al.
Publicado: (2010)

Posttranslational Regulation of Human DNA Polymerase ι
por: McIntyre, Justyna, et al.
Publicado: (2015)

DNA Methylation-mediated Down-regulation of DNA Methyltransferase-1 (DNMT1) Is Coincident with, but Not Essential for, Global Hypomethylation in Human Placenta
por: Novakovic, Boris, et al.
Publicado: (2010)

An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex
por: Hammel, Michal, et al.
Publicado: (2016)

Slow extension of the invading DNA strand in a D-loop formed by RecA-mediated homologous recombination may enhance recognition of DNA homology
por: Lu, Daniel, et al.
Publicado: (2019)

Cooperative Assembly of a Protein-DNA Filament for Nonhomologous End Joining
por: Tsai, Chun J., et al.
Publicado: (2013)

Xenopus laevis Ctc1-Stn1-Ten1 (xCST) Protein Complex Is Involved in Priming DNA Synthesis on Single-stranded DNA Template in Xenopus Egg Extract
por: Nakaoka, Hidenori, et al.
Publicado: (2012)

DNA Replication Dynamics of the GGGGCC Repeat of the C9orf72 Gene
por: Thys, Ryan Griffin, et al.
Publicado: (2015)

DNA Induces Conformational Changes in a Recombinant Human Minichromosome Maintenance Complex
por: Hesketh, Emma L., et al.
Publicado: (2015)

Magnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutS
por: Lebbink, Joyce H. G., et al.
Publicado: (2010)

Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes
por: Clark, Nicholas J., et al.
Publicado: (2012)

Human DNA Polymerase ϵ Is Able to Efficiently Extend from Multiple Consecutive Ribonucleotides
por: Göksenin, A. Yasemin, et al.
Publicado: (2012)

DNA damage recognition /
Publicado: (2006)

DNA Instability Maintains the Repeat Length of the Yeast RNA Polymerase II C-terminal Domain
por: Morrill, Summer A., et al.
Publicado: (2016)

Conserved Overlapping Gene Arrangement, Restricted Expression, and Biochemical Activities of DNA Polymerase ν (POLN)
por: Takata, Kei-ichi, et al.
Publicado: (2015)

Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency
por: Chang, Howard H. Y., et al.
Publicado: (2016)

Spatial organization of DNA sequences directs the assembly of bacterial chromatin by a nucleoid-associated protein
por: Japaridze, Aleksandre, et al.
Publicado: (2017)

A Human PMS2 Homologue from Aquifex aeolicus Stimulates an ATP-dependent DNA Helicase
por: Mauris, Jerome, et al.
Publicado: (2010)

A Conserved Motif in the C-terminal Tail of DNA Polymerase α Tethers Primase to the Eukaryotic Replisome
por: Kilkenny, Mairi L., et al.
Publicado: (2012)

Synthesis of Mitochondrial DNA Precursors during Myogenesis, an Analysis in Purified C2C12 Myotubes
por: Frangini, Miriam, et al.
Publicado: (2013)

DNA and Protein Requirements for Substrate Conformational Changes Necessary for Human Flap Endonuclease-1-catalyzed Reaction
por: Algasaier, Sana I., et al.
Publicado: (2016)

Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast
por: Admiraal, Suzanne J., et al.
Publicado: (2019)

RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA
por: González de Cózar, Jose M., et al.
Publicado: (2019)

The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF
por: Ciccone, David N., et al.
Publicado: (2019)

Activation of CDK4 by Tax chemosensitizes p53-mutant cells to DNA damage
por: Semmes, O John, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_vq6kakmrjgphti50hlc7lau6h3