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NOTCH2 Is Neither Rearranged nor Mutated in t(1;19) Positive Oligodendrogliomas

The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation. Recent studies of 1p/19q co-deleted OD suggest that the NOTCH2 gene is implicated in oligodendrocyte differentiation and may...

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Detalles Bibliográficos
Autores principales: Benetkiewicz, Magdalena, Idbaih, Ahmed, Cousin, Pierre-Yves, Boisselier, Blandine, Marie, Yannick, Crinière, Emmanuelle, Hoang-Xuan, Khê, Delattre, Jean-Yves, Sanson, Marc, Delattre, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606061/
https://www.ncbi.nlm.nih.gov/pubmed/19119320
http://dx.doi.org/10.1371/journal.pone.0004107