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NOTCH2 Is Neither Rearranged nor Mutated in t(1;19) Positive Oligodendrogliomas
The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation. Recent studies of 1p/19q co-deleted OD suggest that the NOTCH2 gene is implicated in oligodendrocyte differentiation and may...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606061/ https://www.ncbi.nlm.nih.gov/pubmed/19119320 http://dx.doi.org/10.1371/journal.pone.0004107 |