Quantification of Mouse Lung Elastin During Prenatal Development

Elastic fibres play a crucial function during the process of lung alveolisation. During the perinatal period, any changes in the elastogenic process during foetal development may result in permanent lifetime defects. In pre-natal life, well-developed pulmonary elastic fibres should favor the pre-nat...

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Detalles Bibliográficos
Autores principales: Rodrigues, Paula, Gonçalves, Carlos, Honório, Ana, Barros, José, Bairos, Vasco
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606651/
https://www.ncbi.nlm.nih.gov/pubmed/19365535
http://dx.doi.org/10.2174/1874306400802010046
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author Rodrigues, Paula
Gonçalves, Carlos
Honório, Ana
Barros, José
Bairos, Vasco
author_facet Rodrigues, Paula
Gonçalves, Carlos
Honório, Ana
Barros, José
Bairos, Vasco
author_sort Rodrigues, Paula
collection PubMed
description Elastic fibres play a crucial function during the process of lung alveolisation. During the perinatal period, any changes in the elastogenic process during foetal development may result in permanent lifetime defects. In pre-natal life, well-developed pulmonary elastic fibres should favor the pre-natal maturation of the lung and an enhanced alveolisation, which in many species, such as humans begins only after birth. The authors present a quantitative study by image analysis and by high-pressure liquid chromatography (HPLC) of the mouse lungs’ elastic fibre content from the 15th till the 19th gestational day.
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spelling pubmed-26066512009-04-10 Quantification of Mouse Lung Elastin During Prenatal Development Rodrigues, Paula Gonçalves, Carlos Honório, Ana Barros, José Bairos, Vasco Open Respir Med J Article Elastic fibres play a crucial function during the process of lung alveolisation. During the perinatal period, any changes in the elastogenic process during foetal development may result in permanent lifetime defects. In pre-natal life, well-developed pulmonary elastic fibres should favor the pre-natal maturation of the lung and an enhanced alveolisation, which in many species, such as humans begins only after birth. The authors present a quantitative study by image analysis and by high-pressure liquid chromatography (HPLC) of the mouse lungs’ elastic fibre content from the 15th till the 19th gestational day. Bentham Open 2008-05-15 /pmc/articles/PMC2606651/ /pubmed/19365535 http://dx.doi.org/10.2174/1874306400802010046 Text en © Rodrigues et al.; Licensee Bentham Open. http://creativecommons.org/license/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/license/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Rodrigues, Paula
Gonçalves, Carlos
Honório, Ana
Barros, José
Bairos, Vasco
Quantification of Mouse Lung Elastin During Prenatal Development
title Quantification of Mouse Lung Elastin During Prenatal Development
title_full Quantification of Mouse Lung Elastin During Prenatal Development
title_fullStr Quantification of Mouse Lung Elastin During Prenatal Development
title_full_unstemmed Quantification of Mouse Lung Elastin During Prenatal Development
title_short Quantification of Mouse Lung Elastin During Prenatal Development
title_sort quantification of mouse lung elastin during prenatal development
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606651/
https://www.ncbi.nlm.nih.gov/pubmed/19365535
http://dx.doi.org/10.2174/1874306400802010046
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AT honorioana quantificationofmouselungelastinduringprenataldevelopment
AT barrosjose quantificationofmouselungelastinduringprenataldevelopment
AT bairosvasco quantificationofmouselungelastinduringprenataldevelopment

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