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Not All Children with Under-Control Asthma are Controlled

Subclinical lung function alterations can sometimes be discovered in asthmatic patients under clinical control. This study aimed to identify the burden of asthmatic children with subclinical airways abnormalities who may benefit from an adjustment in asthma therapy. 134 6-to-17-year-old asthmatic ch...

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Detalles Bibliográficos
Autores principales: Ricci, G, Dondi, A, Calamelli, E, Dell’Omo, V, Pagliara, L, Belotti, T, Masi, M
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606653/
https://www.ncbi.nlm.nih.gov/pubmed/19340318
http://dx.doi.org/10.2174/1874306400802010001
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author Ricci, G
Dondi, A
Calamelli, E
Dell’Omo, V
Pagliara, L
Belotti, T
Masi, M
author_facet Ricci, G
Dondi, A
Calamelli, E
Dell’Omo, V
Pagliara, L
Belotti, T
Masi, M
author_sort Ricci, G
collection PubMed
description Subclinical lung function alterations can sometimes be discovered in asthmatic patients under clinical control. This study aimed to identify the burden of asthmatic children with subclinical airways abnormalities who may benefit from an adjustment in asthma therapy. 134 6-to-17-year-old asthmatic children were enrolled. Of them, 98 presented apparently under clinical control disease and all performed spirometry before and after bronchodilation: 17 (17.3%) had a positive bronchodilation test, in addition to significantly lower lung function indexes as compared to those with under-control asthma who had a negative bronchodilation test. These patients were randomized and re-evaluated: patients (n=8) receiving an adjustment in their therapy showed an improvement in lung function tests and quality of life indexes as compared to 7 without therapy adjustment. In conclusion, a substantial number of apparently-under-control asthmatic children show airways alterations that can be improved by adjusting their therapy, which also seems to enhance their quality of life.
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spelling pubmed-26066532009-04-01 Not All Children with Under-Control Asthma are Controlled Ricci, G Dondi, A Calamelli, E Dell’Omo, V Pagliara, L Belotti, T Masi, M Open Respir Med J Article Subclinical lung function alterations can sometimes be discovered in asthmatic patients under clinical control. This study aimed to identify the burden of asthmatic children with subclinical airways abnormalities who may benefit from an adjustment in asthma therapy. 134 6-to-17-year-old asthmatic children were enrolled. Of them, 98 presented apparently under clinical control disease and all performed spirometry before and after bronchodilation: 17 (17.3%) had a positive bronchodilation test, in addition to significantly lower lung function indexes as compared to those with under-control asthma who had a negative bronchodilation test. These patients were randomized and re-evaluated: patients (n=8) receiving an adjustment in their therapy showed an improvement in lung function tests and quality of life indexes as compared to 7 without therapy adjustment. In conclusion, a substantial number of apparently-under-control asthmatic children show airways alterations that can be improved by adjusting their therapy, which also seems to enhance their quality of life. Bentham Science Publishers Ltd. 2008-02-06 /pmc/articles/PMC2606653/ /pubmed/19340318 http://dx.doi.org/10.2174/1874306400802010001 Text en 2008 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Ricci, G
Dondi, A
Calamelli, E
Dell’Omo, V
Pagliara, L
Belotti, T
Masi, M
Not All Children with Under-Control Asthma are Controlled
title Not All Children with Under-Control Asthma are Controlled
title_full Not All Children with Under-Control Asthma are Controlled
title_fullStr Not All Children with Under-Control Asthma are Controlled
title_full_unstemmed Not All Children with Under-Control Asthma are Controlled
title_short Not All Children with Under-Control Asthma are Controlled
title_sort not all children with under-control asthma are controlled
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606653/
https://www.ncbi.nlm.nih.gov/pubmed/19340318
http://dx.doi.org/10.2174/1874306400802010001
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