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Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity

OBJECTIVE—Osteopontin (OPN) plays an important role in the development of insulin resistance and liver complications in dietary murine models. We aimed to determine the expression pattern of OPN and its receptor CD44 in obese patients and mice according to insulin resistance and liver steatosis. RES...

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Detalles Bibliográficos
Autores principales: Bertola, Adeline, Deveaux, Vanessa, Bonnafous, Stéphanie, Rousseau, Déborah, Anty, Rodolphe, Wakkach, Abdelilah, Dahman, Moncef, Tordjman, Joan, Clément, Karine, McQuaid, Siobhán E., Frayn, Keith N., Huet, Pierre-Michel, Gugenheim, Jean, Lotersztajn, Sophie, Le Marchand-Brustel, Yannick, Tran, Albert, Gual, Philippe
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606860/
https://www.ncbi.nlm.nih.gov/pubmed/18952835
http://dx.doi.org/10.2337/db08-0400