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Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver

OBJECTIVE—To determine whether 1) hepatic ceramide and diacylglycerol concentrations, 2) SCD1 activity, and 3) hepatic lipogenic index are increased in the human nonalcoholic fatty liver. RESEARCH DESIGN AND METHODS—We studied 16 subjects with (n = 8) and without (n = 8) histologically determined no...

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Detalles Bibliográficos
Autores principales:	Kotronen, Anna, Seppänen-Laakso, Tuulikki, Westerbacka, Jukka, Kiviluoto, Tuula, Arola, Johanna, Ruskeepää, Anna-Liisa, Orešič, Matej, Yki-Järvinen, Hannele
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606873/ https://www.ncbi.nlm.nih.gov/pubmed/18952834 http://dx.doi.org/10.2337/db08-1074

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