Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway

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The modes of proliferation and differentiation of neural stem cells (NSCs) are coordinately controlled during development, but the underlying mechanisms remain largely unknown. In this study, we show that the protooncoprotein Myc and the tumor suppressor p19(ARF) regulate both NSC self-renewal and t...

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Detalles Bibliográficos
Autores principales: Nagao, Motoshi, Campbell, Kenneth, Burns, Kevin, Kuan, Chia-Yi, Trumpp, Andreas, Nakafuku, Masato
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606961/
https://www.ncbi.nlm.nih.gov/pubmed/19114593
http://dx.doi.org/10.1083/jcb.200807130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606961/
https://www.ncbi.nlm.nih.gov/pubmed/19114593
http://dx.doi.org/10.1083/jcb.200807130

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