ATR and Chk1 Suppress a Caspase-3–Dependent Apoptotic Response Following DNA Replication Stress

The related PIK-like kinases Ataxia-Telangiectasia Mutated (ATM) and ATM- and Rad3-related (ATR) play major roles in the regulation of cellular responses to DNA damage or replication stress. The pro-apoptotic role of ATM and p53 in response to ionizing radiation (IR) has been widely investigated. Mu...

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Detalles Bibliográficos
Autores principales: Myers, Katie, Gagou, Mary E., Zuazua-Villar, Pedro, Rodriguez, Rene, Meuth, Mark
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607051/
https://www.ncbi.nlm.nih.gov/pubmed/19119425
http://dx.doi.org/10.1371/journal.pgen.1000324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607051/
https://www.ncbi.nlm.nih.gov/pubmed/19119425
http://dx.doi.org/10.1371/journal.pgen.1000324

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