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ATR and Chk1 Suppress a Caspase-3–Dependent Apoptotic Response Following DNA Replication Stress

The related PIK-like kinases Ataxia-Telangiectasia Mutated (ATM) and ATM- and Rad3-related (ATR) play major roles in the regulation of cellular responses to DNA damage or replication stress. The pro-apoptotic role of ATM and p53 in response to ionizing radiation (IR) has been widely investigated. Mu...

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Detalles Bibliográficos
Autores principales:	Myers, Katie, Gagou, Mary E., Zuazua-Villar, Pedro, Rodriguez, Rene, Meuth, Mark
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607051/ https://www.ncbi.nlm.nih.gov/pubmed/19119425 http://dx.doi.org/10.1371/journal.pgen.1000324

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