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Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk

Several lines of evidence implicate mitochondrial dysfunction in the development of cancer. To test the hypothesis that common mtDNA variation influences the risk of colorectal cancer (CRC), we genotyped 132 tagging mtDNA variants in a sample of 2854 CRC cases and 2822 controls. The variants examine...

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Detalles Bibliográficos
Autores principales:	Webb, E, Broderick, P, Chandler, I, Lubbe, S, Penegar, S, Tomlinson, I P M, Houlston, R S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607223/ https://www.ncbi.nlm.nih.gov/pubmed/19050702 http://dx.doi.org/10.1038/sj.bjc.6604805

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