Angiogenesis in pre-malignant conditions

Evidence from human studies suggests that angiogenesis commences during the pre-malignant stages of cancer. Inhibiting angiogenesis may, therefore, be of potential value in preventing progression to invasive cancer. Understanding the mechanisms inducing angiogenesis in these lesions and identificati...

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Detalles Bibliográficos
Autores principales: Menakuru, S R, Brown, N J, Staton, C A, Reed, M W R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607228/
https://www.ncbi.nlm.nih.gov/pubmed/18941463
http://dx.doi.org/10.1038/sj.bjc.6604733
Descripción
Sumario:Evidence from human studies suggests that angiogenesis commences during the pre-malignant stages of cancer. Inhibiting angiogenesis may, therefore, be of potential value in preventing progression to invasive cancer. Understanding the mechanisms inducing angiogenesis in these lesions and identification of those important in human tumourigenesis are necessary to develop translational strategies that will help realise the goal of angioprevention.

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