Cargando…

Fibulin 1 is downregulated through promoter hypermethylation in gastric cancer

Tumour suppressor genes (TSGs) were frequently inactivated through promoter hypermethylation in gastric carcinoma as well as pre-malignant gastric lesions, suggesting that promoter hypermethylation can be used as a marker to define novel TSGs and also biomarkers for early detection of gastric cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Y Y, Jin, H, Liu, X, Siu, J M T, Wong, Y P, Ng, E K O, Yu, J, Leung, W-k, Sung, J J Y, Chan, F K L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607230/ https://www.ncbi.nlm.nih.gov/pubmed/18985039 http://dx.doi.org/10.1038/sj.bjc.6604760

Ejemplares similares

Fibulin-1 Is Downregulated Through Promoter Hypermethylation in Colorectal Cancer: A Consort Study
por: Xu, Zhiying, et al.
Publicado: (2015)

METH-2 silencing and promoter hypermethylation in NSCLC
por: Dunn, J R, et al.
Publicado: (2004)

Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia
por: Honda, T, et al.
Publicado: (2004)

DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers
por: Ying, J, et al.
Publicado: (2009)

Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer
por: Lim, S L, et al.
Publicado: (2008)

Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer
por: Leung, W K, et al.
Publicado: (2005)

DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer
por: Kawakami, K, et al.
Publicado: (2006)

hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations
por: Wang, F, et al.
Publicado: (2010)

Hypermethylation of genes in testicular embryonal carcinomas
por: Cheung, Hoi-Hung, et al.
Publicado: (2016)

Absence of cyclin D2 expression is associated with promoter hypermethylation in gastric cancer
por: Yu, J, et al.
Publicado: (2003)

RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
por: Endoh, M, et al.
Publicado: (2005)

Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers
por: Noda, H, et al.
Publicado: (2007)

Frequent downregulation of 14-3-3 σ protein and hypermethylation of 14-3-3 σ gene in salivary gland adenoid cystic carcinoma
por: Uchida, D, et al.
Publicado: (2004)

Putative tumour suppressor gene necdin is hypermethylated and mutated in human cancer
por: De Faveri, L E, et al.
Publicado: (2013)

Reduced BRCA1 expression due to promoter hypermethylation in therapy-related acute myeloid leukaemia
por: Scardocci, A, et al.
Publicado: (2006)

Overexpression of Betaig-h3 gene downregulates integrin α5β1 and suppresses tumorigenicity in radiation-induced tumorigenic human bronchial epithelial cells
por: Zhao, Y L, et al.
Publicado: (2002)

Genetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression
por: Tan, X, et al.
Publicado: (2013)

High frequency of mitochondrial genome instability in human endometrial carcinomas
por: Liu, V W S, et al.
Publicado: (2003)

Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma
por: Lindsey, J C, et al.
Publicado: (2007)

RASSF1A hypermethylation in pretreatment serum DNA of neuroblastoma patients: a prognostic marker
por: Misawa, A, et al.
Publicado: (2009)

Mutations in the ST7/RAY1/HELG locus rarely occur in primary colorectal, gastric, and hepatocellular carcinomas
por: Yoshimura, S, et al.
Publicado: (2003)

Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line
por: To, K F, et al.
Publicado: (2004)

Differential gene expression profiles of gastric cancer cells established from primary tumour and malignant ascites
por: Sakakura, C, et al.
Publicado: (2002)

Loss of heterozygosity at 9q33 and hypermethylation of the DBCCR1 gene in oral squamous cell carcinoma
por: Gao, S, et al.
Publicado: (2004)

High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer
por: Kim, D-W, et al.
Publicado: (2008)

Gene expression profiles in human gastric cancer: expression of maspin correlates with lymph node metastasis
por: Terashima, M, et al.
Publicado: (2005)

Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis
por: Takeno, A, et al.
Publicado: (2008)

The Wnt antagonist sFRP1 is downregulated in premalignant large bowel adenomas
por: Caldwell, G M, et al.
Publicado: (2006)

Promoter hypermethylation of MGMT, CDH1, RAR-β and SYK tumour suppressor genes in granulosa cell tumours (GCTs) of ovarian origin
por: Dhillon, V S, et al.
Publicado: (2004)

TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations
por: Labussière, M, et al.
Publicado: (2014)

Activating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum
por: Matsubara, A, et al.
Publicado: (2015)

Fibulin-2 inhibits development of gastric cancer by downregulating β-catenin
por: Ma, Hongping, et al.
Publicado: (2019)

Common genetic variability in ESR1 and EGF in relation to endometrial cancer risk and survival
por: Einarsdóttir, K, et al.
Publicado: (2009)

Gene silencing of HPV16 E6/E7 induced by promoter-targeting siRNA in SiHa cells
por: Hong, D, et al.
Publicado: (2009)

Basal core promoter mutation is associated with progression to cirrhosis rather than hepatocellular carcinoma in chronic hepatitis B virus infection
por: Chu, C-M, et al.
Publicado: (2012)

Genetic and epigenetic alterations on the short arm of chromosome 11 are involved in a majority of sporadic Wilms' tumours
por: Satoh, Y, et al.
Publicado: (2006)

Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer
por: Deng, G, et al.
Publicado: (2002)

Functional screening of genes suppressing TRAIL-induced apoptosis: distinct inhibitory activities of Bcl-X(L) and Bcl-2
por: Kim, I-K, et al.
Publicado: (2003)

Genetic and epigenetic alterations of Ras signalling pathway in colorectal neoplasia: analysis based on tumour clinicopathological features
por: Harada, K, et al.
Publicado: (2007)

Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer
por: Rimkus, C, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_7q7qpoihjqbo345trtrnhg2kjg