Cargando…

PPARγ agonists inhibit growth and expansion of CD133+ brain tumour stem cells

Brain tumour stem cells (BTSCs) are a small population of cells that has self-renewal, transplantation, multidrug resistance and recurrence properties, thus remain novel therapeutic target for brain tumour. Recent studies have shown that peroxisome proliferator-activated receptor gamma (PPARγ) agoni...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chearwae, W, Bright, J J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607234/ https://www.ncbi.nlm.nih.gov/pubmed/19018263 http://dx.doi.org/10.1038/sj.bjc.6604786

Ejemplares similares

Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery
por: Fang, D D, et al.
Publicado: (2010)

PPARγ Agonists Promote Oligodendrocyte Differentiation of Neural Stem Cells by Modulating Stemness and Differentiation Genes
por: Kanakasabai, Saravanan, et al.
Publicado: (2012)

PPARγ agonists regulate the expression of stemness and differentiation genes in brain tumour stem cells
por: Pestereva, E, et al.
Publicado: (2012)

Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer
por: Lugli, A, et al.
Publicado: (2010)

CD133 expression is an independent prognostic marker for low survival in colorectal cancer
por: Horst, D, et al.
Publicado: (2008)

CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer
por: Maeda, S, et al.
Publicado: (2008)

A truncated form of CD9-partner 1 (CD9P-1), GS-168AT2, potently inhibits in vivo tumour-induced angiogenesis and tumour growth
por: Colin, S, et al.
Publicado: (2011)

The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer
por: Yoshino, H, et al.
Publicado: (2011)

Isolation of tumour stem-like cells from benign tumours
por: Xu, Q, et al.
Publicado: (2009)

Expression of interferon-γ in human adrenal gland and kidney tumours
por: Li, Q, et al.
Publicado: (2007)

Activation of JNK and high expression level of CD133 predict a poor response to sorafenib in hepatocellular carcinoma
por: Hagiwara, S, et al.
Publicado: (2012)

miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer
por: Chiyomaru, T, et al.
Publicado: (2010)

Tumour-infiltrating CD4(+) and CD8(+) lymphocytes as predictors of clinical outcome in glioma
por: Han, S, et al.
Publicado: (2014)

Dual roles of tumour cells-derived matrix metalloproteinase 2 on brain tumour growth and invasion
por: Yu, Ching-Fang, et al.
Publicado: (2017)

An immunohistochemical perspective of PPARβ and one of its putative targets PDK1 in normal ovaries, benign and malignant ovarian tumours
por: Ahmed, N, et al.
Publicado: (2008)

Objective assessment of tumour response to therapy based on tumour growth kinetics
por: Mehrara, E, et al.
Publicado: (2011)

Expression of laminin 5-γ2 chain in cutaneous squamous cell carcinoma and its role in tumour invasion
por: Hamasaki, H, et al.
Publicado: (2011)

CD9P-1 expression correlates with the metastatic status of lung cancer, and a truncated form of CD9P-1, GS-168AT2, inhibits in vivo tumour growth
por: Guilmain, W, et al.
Publicado: (2011)

Tumour-infiltrating CD68+ and CD57+ cells predict patient outcome in stage II–III colorectal cancer
por: Chaput, N, et al.
Publicado: (2013)

Suppression of tumour growth by orally administered osteopontin is accompanied by alterations in tumour blood vessels
por: Rittling, S R, et al.
Publicado: (2014)

TAp63 suppress metastasis via miR-133b in colon cancer cells
por: Lin, C W, et al.
Publicado: (2014)

CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a ‘pro-/anti-tumour’ approach to tumour host interaction in colorectal cancer
por: Lugli, A, et al.
Publicado: (2009)

Constitutive androstane receptor agonist CITCO inhibits growth and expansion of brain tumour stem cells
por: Chakraborty, S, et al.
Publicado: (2011)

IKKα is required in the intestinal epithelial cells for tumour stemness
por: Colomer, Carlota, et al.
Publicado: (2018)

PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients
por: Wu, X, et al.
Publicado: (2014)

MYB is a novel regulator of pancreatic tumour growth and metastasis
por: Srivastava, Sanjeev K, et al.
Publicado: (2015)

Δ133p53 is an independent prognostic marker in p53 mutant advanced serous ovarian cancer
por: Hofstetter, G, et al.
Publicado: (2011)

Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer
por: Rao, S R, et al.
Publicado: (2017)

Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer
por: Seo, A N, et al.
Publicado: (2013)

MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1
por: Feng, Y, et al.
Publicado: (2014)

Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse
por: Kahlert, C, et al.
Publicado: (2009)

Identification of novel growth factor-responsive genes in neuroendocrine gastrointestinal tumour cells
por: Hofsli, E, et al.
Publicado: (2005)

Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer
por: Ryan, A J, et al.
Publicado: (2009)

Underexpression of peroxisome proliferator-activated receptor (PPAR)γ in PAX8/PPARγ-negative thyroid tumours
por: Marques, A R, et al.
Publicado: (2004)

Tumour-associated CD66b(+) neutrophil count is an independent prognostic factor for recurrence in localised cervical cancer
por: Carus, A, et al.
Publicado: (2013)

Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells
por: Kraan, J, et al.
Publicado: (2014)

HIF2α is involved in the expansion of CXCR4-positive cancer stem-like cells in renal cell carcinoma
por: Micucci, Carla, et al.
Publicado: (2015)

Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis
por: Lee, Y S, et al.
Publicado: (2012)

The relationship between tumour budding, the tumour microenvironment and survival in patients with invasive ductal breast cancer
por: Gujam, F J A, et al.
Publicado: (2015)

Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer
por: Kaneda, H, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_m7gd46l8m0bmurri4e6f2ueg5v