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Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells

BACKGROUND: Chemoresistance is a serious problem in pancreatic cancer, but the mechanism of resistance and strategies against the resistance have not been elucidated. We examined the potential of the phosphatidylinositol 3-kinase (PI3K)/Akt inhibitor LY294002 to enhance the anti-tumor effect of cisp...

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Detalles Bibliográficos
Autores principales:	Fujiwara, Masao, Izuishi, Kunihiko, Sano, Takanori, Hossain, Mohammad Akram, Kimura, Shoji, Masaki, Tsutomu, Suzuki, Yasuyuki
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607265/ https://www.ncbi.nlm.nih.gov/pubmed/19032736 http://dx.doi.org/10.1186/1756-9966-27-76

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