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Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet

BACKGROUND: Astrocytomas are largely dependent on glycolysis to satisfy their bioenergetic requirements for growth and survival. Therapies that target glycolysis can potentially manage astrocytoma growth and progression. Dietary restriction of the high fat/low carbohydrate ketogenic diet (KD-R) redu...

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Detalles Bibliográficos
Autores principales: Marsh, Jeremy, Mukherjee, Purna, Seyfried, Thomas N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607273/
https://www.ncbi.nlm.nih.gov/pubmed/19032781
http://dx.doi.org/10.1186/1743-7075-5-33