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Few alterations in clinical pathology and histopathology observed in a CYP2C18&19 humanized mice model
BACKGROUND: This study was performed to characterize a gene-addition transgenic mouse containing a BAC (bacterial artificial chromosome) clone spanning the human CYP2C18&19 genes (tg-CYP2C18&19). METHODS: Hemizygous tg-CYP2C18&19, 11 week old mice were compared with wild-type littermates...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607276/ https://www.ncbi.nlm.nih.gov/pubmed/19038035 http://dx.doi.org/10.1186/1751-0147-50-47 |