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ElliPro: a new structure-based tool for the prediction of antibody epitopes

BACKGROUND: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between antigenicity, solvent accessibility, and flexibility in proteins was demonstrated. Subsequently, Thornton and colleagues p...

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Detalles Bibliográficos
Autores principales: Ponomarenko, Julia, Bui, Huynh-Hoa, Li, Wei, Fusseder, Nicholas, Bourne, Philip E, Sette, Alessandro, Peters, Bjoern
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2607291/
https://www.ncbi.nlm.nih.gov/pubmed/19055730
http://dx.doi.org/10.1186/1471-2105-9-514